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ESTUDIO CIENTÍFICO
Cetylpyridinium chloride promotes disaggregation of SARS-CoV-2 virus-like particles
Autores: Manuel Bañó-Polo, Luis Martínez-Gil, Manuel M. Sánchez del Pino, Alberto Massoli, Ismael Mingarro, Rubén Léon & Maria Jesus Garcia-Murria
Publicado en: Journal of Oral Microbiology
Año de publicación: 2022
INTRODUCCIÓN
Background SARS-CoV-2 is continuously disseminating worldwide. The development of strategies to break transmission is mandatory.
OBJETIVOS
To investigate the potential of cetylpyridinium chloride (CPC) as a viral inhibitor.
MATERIALES
SARS-CoV-2 Virus Like-Particles (VLPs) were incubated with CPC, a potent surfactant routinely included in mouthwash preparations.
RESULTADOS
Concentrations of 0.05% CPC (w/v) commonly used in mouthwash preparations are sufficient to promote the rupture of SARS-CoV-2 VLP membranes.
CONCLUSIONES
Including CPC in mouthwashes could be a prophylactic strategy to keep SARS-CoV-2 from spreading.
MATERIALES DESCARGABLES
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